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1. Gabrielsen, M.; Kurczab, R.; Siwek, A.; Wolak, M.; Ravna AW.; Kristiansen, K.; Kufareva, I.; Abagyan, R.; Nowak, G.; Chilmonczyk, Z.; Sylte, I.; Bojarski, A. J. Identification of novel serotonin transporter compounds by virtual screening. J. Chem. Inf. Model. 2014, 54, 933-944. PMID: 24521202

2. Waszkielewicz, A. M.; Gunia, A.; Szkaradek, N.; Pytka, K.; Siwek, A.; Satala, G.; Bojarski, A. J.; Szneler, E.; Marona, H. Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety. Bioorg. Med. Chem. Lett. 2013, 23, 4419-4423. PMID: 23787101

3. Gabrielsen, M.; Wolosewicz, K.; Zawadzka, A.; Kossakowski, J.; Nowak, G.; Wolak, M.; Stachowicz, K.; Siwek, A.; Ravna, A. W.; Kufareva, I.; Kozerski, L.; Bednarek, E.; Sitkowski, J.; Bocian, W.; Abagyan, R.; Bojarski, A. J.; Sylte, I.; Chilmonczyk, Z. Synthesis, Antidepressant Evaluation and Docking Studies of Long-Chain Alkylnitroquipazines as Serotonin Transporter Inhibitors. Chem. Biol. Drug Des 2013, 81, 695-706. PMID: 23574807

4. Chlon-Rzepa, G.; Zmudzki, P.; Satala, G.; Duszynska, B.; Partyka, A.; Wrobel, D.; Jastrzebska-Wiesek, M.; Wesolowska, A.; Bojarski, A. J.; Pawlowski, M.; Zajdel, P. New 8-aminoalkyl derivatives of purine-2,6-dione with arylalkyl, allyl or propynyl substituents in position 7, their 5-HT1A, 5-HT2A, and 5-HT7 receptor affinity and pharmacological evaluation. Pharmacol. Rep. 2013, 65, 15-29. PMID: 23563020

5. Grychowska, K.; Marciniec, K.; Canale, V.; Szymiec, M.; Glanowski, G.; Satala, G.; Maslankiewicz, A.; Pawlowski, M.; Bojarski, A. J.; Zajdel, P. Quinolinesulfonamides of Aryloxy-/Arylthio-ethyl Piperidines: Influence of an Arylether Fragment on 5-HT1A /5-HT7 Receptor Selectivity. Arch. Pharm. (Weinheim). 2013, 346, 180-188. PMID: 23381952

6. Obniska, J.; Chlebek, I.; Kamiński, K.; Bojarski, A. J.; Satala, G. Anticonvulsant Activity and 5-HT1A/5-HT7 Receptors Affinity of Piperazine Derivatives of 3,3-Diphenyl- and 3,3-Dimethyl-succinimides. Lett. Drug Des. Discov. 2013, 10, 173-182.

7. Zajdel, P.; Marciniec, K.; Maslankiewicz, A.; Grychowska, K.; Satala, G.; Duszynska, B.; Lenda, T.; Siwek, A.; Nowak, G.; Partyka, A.; Wrobel, D.; Jastrzebska-Wiesek, M.; Bojarski, A. J.; Wesolowska, A.; Pawlowski, M. Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT(1A)/5-HT(2A)/5-HT(7) and dopamine D(2)/D(3) receptors. Eur. J. Med. Chem. 2013, 60, 42-50. PMID: 23279866

8. Zajdel, P.; Kurczab, R.; Grychowska, K.; Satała, G.; Pawłowski, M.; Bojarski, A. J. The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT7 receptor antagonists. Eur. J. Med. Chem. 2012, 56, 348-360. PMID: 22926225

9. Obniska, J.; Chlebek, I.; Kamiński, K.; Bojarski, A. J.; Satała, G. Synthesis, anticonvulsant activity and 5-HT1A/5-HT7 receptors affinity of 1-[(4-arylpiperazin-1-yl)-propyl]-succinimides. Pharmacol. Rep. 2012, 64, 326-336. PMID: 22661183

10. Zajdel, P.; Marciniec, K.; Maslankiewicz, A.; Satala, G.; Duszynska, B.; Bojarski, A. J.; Partyka, A.; Jastrzebska-Wiesek, M.; Wrobel, D.; Wesolowska, A.; Pawlowski, M. Quinoline- and isoquinoline-sulfonamide derivatives of LCAP as potent CNS multi-receptor-5-HT1A/5-HT2A/5-HT7 and D2/D3/D4-agents: the synthesis and pharmacological evaluation. Bioorg. Med. Chem. 2012, 20, 1545-1556. PMID: 22277589

11. Jaronczyk, M.; Wolosewicz, K.; Gabrielsen, M.; Nowak, G.; Kufareva, I.; Mazurek, A. P.; Ravna, A. W.; Abagyan, R.; Bojarski, A. J.; Sylte, I.; Chilmonczyk, Z. Synthesis, in vitro binding studies and docking of long-chain arylpiperazine nitroquipazine analogues, as potential serotonin transporter inhibitors. Eur. J. Med. Chem. 2012, 49C, 200-210. PMID: 22309909

12. Witowska-Jarosz, J.; Jaronczyk, M.; Mazurek, A. P.; Sylte, I.; Bojarski, A. J.; Chilmonczyk, Z.; Jarosz, M. Mass-spectrometric studies of new 6-nitroquipazines-serotonin transporter inhibitors. Anal. Bioanal. Chem. 2012, 402, 537-541. PMID: 21960253

13. Gabrielsen, M.; Kurczab, R.; Ravna, A. W.; Kufareva, I.; Abagyan, R.; Chilmonczyk, Z.; Bojarski, A. J.; Sylte, I. Molecular mechanism of serotonin transporter inhibition elucidated by a new flexible docking protocol. Eur. J. Med. Chem. 2012, 47, 24-37. PMID: 22071255

14. Gabrielsen, M.; Ravna, A.W.; Kristiansen, K.; Sylte, I. Substrate binding and translocation of the serotonin transporter studied by docking and molecular dynamics simulations. J. Mol. Model. 2012, 18, 1073-1085. PMID: 21670993

15. Mordalski, S.; Kosciolek, T.; Kristiansen, K.; Sylte, I.; Bojarski, A. J. Protein binding site analysis by means of structural interaction fingerprint patterns. Bioorg. Med. Chem. Lett. 2011, 21, 6816-6819. PMID: 21974955

16. Zajdel, P.; Marciniec, K.; Maslankiewicz, A.; Paluchowska, M. H.; Satala, G.; Partyka, A.; Jastrzebska-Wiesek, M.; Wrobel, D.; Wesolowska, A.; Duszynska, B.; Bojarski, A. J.; Pawlowski, M. Arene- and quinoline-sulfonamides as novel 5-HT(7) receptor ligands. Bioorg. Med. Chem. 2011, 19, 6750-6759. PMID: 22001327

17. Zajdel, P.; Król, J.; Grychowska, K.; Pawłowski, M.; Subra, G.; Nomezine, G.; Martinez, J.; Satała, G.; Bojarski, A. J.; Zhou, Z.; O'Donnel, M. J.; Scott, W. L. Solid-Phase Synthesis of Arylpiperazine Derivatives and Implementation of the Distributed Drug Discovery (D3). Molecules 2011, 16, 4104-4121.

18. Wierońska, J.M.; Stachowicz, K.; Nowak, G.; Pilc, A. The Loss of Glutamate-GABA Harmony in Anxiety Disorders, Vladimir Kalinin (Ed.), 2011, ISBN: 978-953-307-592-1, InTech.

19. Kurczab, R.; Nowak, M.; Chilmonczyk, Z.; Sylte, I.; Bojarski, A. J. The development and validation of a novel virtual screening cascade protocol to identify potential serotonin 5-HT(7)R antagonists. Bioorg. Med. Chem. Lett. 2010, 20, 2465-2468. PMID: 20346662

20. Wierońska, J.M.; Stachowicz, K.; Pałucha-Poniewiera, A.; Acher, F.; Brański, P.; Pilc, A. Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems. Neuropharmacology. 2010, 59, 627-634. PMID: 20713068

 
 
     
Project PNRF –103–AI-1/07 is supported by a grant from Norway through the Norwegian Financial Mechanism within Polish-Norwegian Research Fund
 
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